Journal Guide

The Journal of Molecular Histology publishes 6 times a year full-length original research papers, review articles, short communications and letters to the editors. Coverage includes studies describing novel cellular or ultrastructural distributions of molecules which provide insight into biochemical or physiological function, development, histological structure and disease processes. Among the techniques addressed are histochemistry, immunohistochemistry, in situ hybridization, receptor binding, autoradiography, image capture and processing, and reporter molecules as well as state-of-the-art visualization techniques. Areas of research include: Cell-Cell and Cell-Matrix Interactions; Connective Tissues; Development and Disease; Neuroscience. The Journal of Molecular Histology does not consider manuscripts dealing with the application of immunological or other probes on non-standard laboratory animal models unless the results are clearly of significant and general biological importance.

Journal of Molecular Signaling will encompass all the molecular aspects of cell signaling involving receptors, G-proteins, kinases, phosphatases, and transcription factors in regulating cell proliferation, differentiation, apoptosis, and oncogenesis in mammalian cells.

The Journal of Molecular and Cellular Cardiology publishes work advancing knowledge of the mechanisms responsible for both normal and diseased cardiovascular function. To this end papers are published in all relevant areas. These include (but are not limited to): structural biology; genetics; proteomics; morphology; stem cells; molecular biology; metabolism; biophysics; electrophysiology; pharmacology and physiology. Papers are encouraged with both basic and translational approaches. The journal is directed not only to basic scientists but also to clinical cardiologists who wish to follow the rapidly advancing frontiers of basic knowledge of the heart and circulation.US National Institutes of Health (NIH) voluntary posting ("Public Access") policyJournal of Molecular and Cellular Cardiology and Elsevier facilitate the author's response to the NIH Public Access Policy. For more details please see the Guide for authors

The Journal of Muscle Research and Cell Motility has as its main aim the publication of original research which bears on either the excitation and contraction of muscle, the analysis of any one of the processes involved therein, or the processes underlying contractility and motility of animal and plant cells. Coverage includes concise theoretical essays which suggest practical approaches for their testing. The journal also publishes full-length Reviews and short News and Views items, Book Reviews, and abstracts from and reports of meetings.

This widely respected journal presents the latest laboratory and clinical studies on biological receptors and associated signal transduction pathways for ligands involved in the regulation of central and peripheral tissues and cells, including the immune system, thus covering the field from neurotransmitters to peptides, steroids, growth factors, cytokines and drugs. The Journal of Receptors and Signal Transduction rapidly communicates important research results to the international scientific community in a variety of stimulating formats, including original and review papers, brief communications, solicited and unsolicited mini reviews, and symposia proceedings. The Journal of Receptors and Signal Transduction maintains a rigorous peer-review process that ensures the originality, timeliness, and significance of topics covered, such as: * pharmacology of receptors and channels * physicochemical and biophysical properties * modeling * molecular biology and genetics * structure and function of receptors and channels * signal transduction pathways * pathology of receptors and channels * molecular strategies for designing drugs acting on receptors * receptors in the diagnosis and therapy of disease and much more!.

The Journal of Steroid Biochemistry and Molecular Biology is devoted to new experimental and theoretical developments in areas related to steroids. The Journal publishes a variety of contributions, including original articles, general and focused reviews, and rapid communications (brief articles of particular interest and clear novelty). Selected cutting-edge topics will be addressed in Special Issues managed by Guest Editors. Special Issues will contain both commissioned reviews and invited original research to provide comprehensive coverage of specific topics, and all articles will undergo rigorous peer-review prior to publication. The JSBMB publishes experimental work, review articles and letters (commentaries).Manuscripts relating to unsolved issues in genetics, molecular biology, biochemistry, structural biology, steroid chemistry, cell biology, molecular medicine, and clinical medicine, are encouraged. Both basic and clinical areas of research are within the scope of the Journal, provided they address mechanisms or yield a functional explanation of processes involving steroids. A further aim of the Journal is to provide steroid-related tools, synthesis and analysis methods, and reference data.Contributions on case studies or descriptions of new compounds should provide new functional data. Otherwise they will be not considered. Reports on translational research are encouraged.The aims of the Journal cover studies on steroid signal transduction pathways, functional annotation of genes and kinetics of metabolic pathways, as well as the creation of enduring and validated resources for metabolomics and systems biology analyses. Furthermore, the Journal also publishes results on lipid research, functional association studies or 'omics' that are instrumental in our understanding of common complex human diseases like metabolic syndrome, diabetes or obesity. Further aspects like steroid-related cancers or neurosteroids are within the scope of the Journal. The Journal aims to enhance our understanding, and the development of approaches to study, the interplay between the environment, genomes, metabolism and disease.Studies that are based on observations performed in a single cell line will not generally be viewed favourably for publication. The experiments should ideally include experiments with comparable cell lines to demonstrate generality or specificity of the effects or mechanisms.US National Institutes of Health (NIH) voluntary posting ("Public Access") policyJournal of Steroid Biochemistry and Molecular Biology and Elsevier facilitate the author's response to the NIH Public Access Policy. For more details please see the Guide for authors

The Journal of Structural Biology publishes papers dealing with the structural analysis of living material at every level of organization by all methods that lead to an understanding of biological function in terms of molecular and supermolecular structure.Techniques covered include:• Light microscopy including confocal microscopy• All types of electron microscopy• X-ray diffraction• Nuclear magnetic resonance• Scanning force microscopy, scanning probe microscopy, and tunneling microscopy• Digital image processing• Computational insights into structureThe field covered by the journal extends from the structural organization of cells and tissues, their membranes, compartments, organelles and supramolecular assemblies, to the structure and conformation of proteins and nucleic acids from the molecular to the atomic level.

Journal of Tissue Engineering and Regenerative Medicine publishes rapidly and rigorously peer-reviewed research papers, reviews, clinical case reports, perspectives, and short communications on topics relevant to the development of therapeutic approaches which combine stem or progenitor cells, biomaterials and scaffolds, growth factors and other bioactive agents, and their respective constructs. All papers should deal with research that has a direct or potential impact on the development of novel clinical approaches for the regeneration or repair of tissues and organs. The journal is multidisciplinary, covering the combination of the principles of life sciences and engineering in efforts to advance medicine and clinical strategies. The journal focuses on the use of cells, materials, and biochemical/mechanical factors in the development of biological functional substitutes that restore, maintain, or improve tissue or organ function. The journal publishes research on any tissue or organ and covers all key aspects of the field, including the development of new biomaterials and processing of scaffolds; the use of different types of cells (mainly stem and progenitor cells) and their culture in specific bioreactors; studies in relevant animal models; and clinical trials in human patients performed under strict regulatory and ethical frameworks. Manuscripts describing the use of advanced methods for the characterization of engineered tissues are also of special interest to the journal readership.

Laboratory Investigation is an international journal owned by the United States and Canadian Academy of Pathology (USCAP) whose prime mission is to publish original manuscripts and review articles in the broad area of translational and basic research as is related to experimental pathology. Manuscripts dealing with research relevance to human clinical disease are given high priority along with those which explore mechanism and etiology of disease processes.The journal features the following types of papers: * Editorial * Inside Lab Invest * Pathobiology in Focus * Perspective * Letter to the Editor * Minireview * Research Articles * Technical Reports.

Lipids focuses on excellent orginal articles and communications as well as invited reviews in the general area of lipid research, including chemistry, biochemistry, clinical nutrition, and metabolism.  In addition, Lipids publishes papers establishing novel methods for addressing research questions in the field of lipid research.

Matrix Biology publishes Regular Research Papers, Brief Reports, Mini Reviews, Landmark Essays, Full Length Reviews and Announcements.Regular Research PapersMatrix Biology will review for publication studies utilizing most scientific technologies including molecular biology, cell biology, immunochemistry, structural biology, computational biology, theoretical biology, and macromolecular chemistry where the subject is extra cellular matrix or is substantially related to matrix and its biological role. The journal will publish articles that are scientifically rigorous, complete within some logical framework, address molecular or cellular mechanisms, and present results that are timely and above average significance. Methods without application to a significant project and data on a new species or system similar to results already in the literature will not be accepted as a regular paper but may be suitable as a Short Note.Brief ReportsMatrix Biology will also review for publication brief reports that meet the same standards of quality and field of interest as regular papers but have a narrower scope and more focused interest. Examples are: DNA sequence from a new species of special interest where the sequence from another species is in the literature; a probe, assay or method that is particularly novel and useful; a new mutation that broadens understanding in a genetic disease where other mutations are known; and brief results of more than usual interest that will be followed by a more detailed study.Mini ReviewsThe aims of the reviews are to: (a) summarize the general concepts in the field; (b) provide a brief summary of the new information in the field; and (c) define unresolved questions and disagreements about currently available data. The mini-reviews will be of two different types, single mini-reviews that will summarize some new and important discovery in the field, and cluster mini-reviews on a topic that has been under investigation for some time. To ensure that the mini-reviews reflect a consensus to the scientists in the field, they will be published in one or two issues as series of articles consisting of (a) an Introductory Review by a Special Editor selected for the series; (b) two or more specialized reviews from two or more additional experts in the field and (c) Letters-to-the-Editor by additional experts in the field who will be invited to comment or volunteer to comment on specific issues raised in the reviews.Landmark EssaysFull Length ReviewsThese are invited comprehensive summaries and analyses of topics that have been under investigation for some time.AnnouncementsAnnouncements of national or international meetings may be published in Matrix Biology.

Mechanisms of Ageing and Development is a multidisciplinary journal aimed at revealing the molecular, biochemical, and biological mechanisms that underlie the process of ageing and the development of age-associated disease. Emphasis is placed on investigations that delineate the contribution of (1) oxidative damage and/or cellular metabolism; (2) genetic instability; (3) telomere integrity; (4) mitochondrial function; (5) genetic programs.Not of interest are (1) studies on age changes that are purely descriptive and which do not address the underlying mechanisms; (2) psychological or social case studies and reports. Manuscripts in basic research areas relevant to the aims and scope are welcomed.Benefits to authorsWe also provide many author benefits, such as free PDFs, a liberal copyright policy, special discounts on Elsevier publications and much more. Please click here for more information on our author services.Please see our Guide for Authors for information on article submission. If you require any further information or help, please visit our support pages: http://support.elsevier.com

We are entering a new and exciting era of microbiological study and application. Recent advances in the now established disciplines of genomics, proteomics, and bioinformatics, together with extensive cooperation between academic and industrial concerns, have brought about an integration of basic and applied microbiology as never before. Microbial Physiology aims to reflect this development by publishing original research papers from all areas of microbiology and biotechnology. It also features written symposia on selected topics, timely reviews, and mini-reviews. Theoretical approaches and descriptions of novel, microbiologically relevant software are also considered. Contributions and ideas from large segments of the scientific community are welcome to make Microbial Physiology a viable, much needed, and up-and-coming forum for current basic and applied microbiological research.